Selected Publications

Demyelination Diseases and Neuropathic Pain Projects

The first official Neurolinx Research Institute affiliated publication (2011), explaining pathological changes in axonal excitability through dynamical analysis of conductance-based models:

 J.S. Coggan, G.K. Ocker, T.J. Sejnowski, S.A. Prescott, Explaining pathological changes in axonal excitability through dynamical analysis of conductance-based models. J Neural Eng. 2011 Dec;8(6):065002. doi: 10.1088/1741-2560/8/6/065002. Epub 2011 Nov 4.

  J.S. Coggan, S.A. Prescott, T.M. Bartol, T.J. Sejnowski, Imbalance of ionic conductances contributes to diverse symptoms of demyelination, Proc Natl Acad Sci U S A. 2010 Nov 30;107(48):20602-9. doi: 10.1073/pnas.1013798107. Epub 2010 Oct 25.

Theory of Myelin Evolution

Proposed changes in the evolution of myelin:

  K.M. Stiefel, B. Torben-Nielsen, J.S. Coggan, Proposed evolutionary changes in the role of myelin . Front Neurosci. 2013 Nov 8;7:202. doi: 10.3389/fnins.2013.00202. eCollection 2013.

Computational Modeling

Evidence for ectopic neurotransmission at a neuronal synapse:

  J.S. Coggan, T.M. Bartol, E. Esquenazi, J.R. Stiles, S. Lamont, M.E. Martone, D.K. Berg, M.H. Ellisman, T.J. Sejnowski, Evidence for ectopic neurotransmission at a neuronal synapse.. Science. 2005 Jul 15;309(5733):446-51.

Open Worm Project

  A. Palyanov, S. Khayrulin, S. D. Larson, A. Dibert, Towards a virtual C. elegans: A framework for simulation and visualization of the neuromuscular system in a 3D physical environment, In Silico Biol. 2011-2012;11(3-4):137-47. doi: 10.3233/ISB-2012-0445.

  G. Idili, M. Cantarelli, M. Buibas, T. Busbice, J.S. Coggan, C. Grove, S. Khayrulin, A. Palyanov, S.D. Larson, Managing Complexity in Multi-Algorithm, Multi-Scale Biological Simulations: An Integrated Software Engineering and Neuroinformatics Approach., Neuroinformatics 2012 Abstract Book.

Green Neuroscience Laboratory

 A. Lam, and E.L. Ohayon. On Building a Greener Neuroscience. Session 171: Neurotechnologies, Neuroethics, and Neuro-Identities: II. Society for Social Studies of Science (4S) Annual Meeting Program (2013) p. 143. San Diego, CA.

 E. L. Ohayon, T. Chailangkarn, A. R. Muotri, P. V. Chu, A. R. Munoz, U. Bellugi, T. J. Sejnowski, and A. Lam. Imaging Metal Distribution in Williams Syndrome Spatially and Across Time: From Cultured Cells to Postmortem Brain Tissue. Society for Neuroscience Abstracts (2013) 482.04. San Diego, CA.

 A. Lam, C. M. Florez, B. D. Kocar, S. M. Webb, L. Frutos, S. Mylvaganam, T. Valiante, P. L. Carlen, and E. L. Ohayon. Quantifying metal distributions using synchrotron x-ray fluorescence imaging of hippocampal tissue resected in human epilepsy surgery. Society for Neuroscience Abstracts (2013) 535.17. San Diego, CA.

 A.K. Lee, A. Lam, and E.L. Ohayon. Developing an Open Source Model for Studying Embodied Cognition and its Relationship to Spatial Neural Networks. Society for Neuroscience Abstracts (2013) 797.12. San Diego, CA.